BDBM202682 US10245267, Example 38::US10709712, Example 38::US9242969, 27::US9694016, 27

SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(nc(n1)S(C)(=O)=O)N1CCOCC1

InChI Key InChIKey=BDMRXFODCGLAFM-UHFFFAOYSA-N

Data  38 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202682   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM202682(US10245267, Example 38 | US10709712, Example 38 | ...)
Affinity DataIC50:  0.860nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent